Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CLPP | Q16740 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26099326 | 0.91 | ALDH1A1 (0.67) | ALDH1A1TP53LMNAGAAMAPT | |
| SCHEMBL26096890 | 0.90 | ALDH1A1 (0.58) | ALDH1A1TP53LMNAGAAMAPT | |
| SCHEMBL26099035 | 0.90 | ALDH1A1 (0.62) | ALDH1A1TP53LMNAGAAMAPT | |
| SCHEMBL26100053 | 0.90 | ALDH1A1 (0.72) | ALDH1A1TP53LMNAGAAMAPT | |
| SCHEMBL26099522 | 0.89 | ALDH1A1 (0.61) | ALDH1A1TP53LMNAGAAMAPT | |
| SCHEMBL26099168 | 0.85 | MAPT (0.76) | ALDH1A1TP53LMNAGAAMAPT | |
| SCHEMBL26098359 | 0.84 | MAPT (0.60) | ALDH1A1TP53LMNAGAAMAPT | |
| SCHEMBL26099897 | 0.84 | MAPT (0.61) | ALDH1A1TP53LMNAGAAMAPT | |
| SCHEMBL26096141 | 0.84 | MAPT (0.61) | ALDH1A1TP53LMNAGAAMAPT | |
| SCHEMBL26097611 | 0.84 | MAPT (0.57) | ALDH1A1TP53LMNAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12370183-B2 | Compositions and methods for treating malaria | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2025-07-29 | — | — | US | disclosed |
| US-20230139910-A1 | COMPOSITIONS AND METHODS FOR TREATING MALARIA | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2023-05-04 | — | — | US | disclosed |
| US-20230139910-A1 | COMPOSITIONS AND METHODS FOR TREATING MALARIA | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2023-05-04 | — | — | US | disclosed |
| US-20230139910-A1 | COMPOSITIONS AND METHODS FOR TREATING MALARIA | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12370183-B2 | Compositions and methods for treating malaria | G6PD, QDPR, FASN | ALDH1A1 1569/4885TP53 4568/4885LMNA 969/4885 |
| US-20230139910-A1 | COMPOSITIONS AND METHODS FOR TREATING MALARIA | G6PD, QDPR, FASN | ALDH1A1 1569/4885TP53 4568/4885LMNA 969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.