Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5847918 | 0.95 | LTB4R (0.41) | SMYD2CYP3A4HTTSMN1; SMN2LTB4R | |
| SCHEMBL4271454 | 0.89 | SMYD2 (0.38) | SMYD2CYP3A4HTTSMN1; SMN2LTB4R | |
| SCHEMBL12192743 | 0.89 | ALDH1A1 (0.40) | SMYD2CYP3A4HTTSMN1; SMN2LTB4R | |
| SCHEMBL12921004 | 0.88 | SMYD2 (0.42) | SMYD2CYP3A4HTTSMN1; SMN2LTB4R | |
| SCHEMBL5136846 | 0.87 | SOAT1 (0.43) | CYP3A4LTB4RPPARAKMT2A | |
| SCHEMBL14265480 | 0.87 | SOAT1 (0.43) | CYP3A4LTB4RPPARAKMT2A | |
| SCHEMBL8403713 | 0.87 | SMYD2 (0.37) | SMYD2CYP3A4HTTSMN1; SMN2LTB4R | |
| SCHEMBL26102243 | 0.87 | SMYD2 (0.35) | SMYD2CYP3A4HTTSMN1; SMN2LMNA | |
| SCHEMBL12503798 | 0.85 | LMNA (0.49) | SMYD2CYP3A4HTTSMN1; SMN2LMNA | |
| SCHEMBL26100458 | 0.85 | LMNA (0.42) | CYP3A4HTTSMN1; SMN2LTB4RLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023076849-A1 | INHIBITORS OF EPIDERMAL GROWTH FACTOR RECEPTOR | ORIC PHARMACEUTICALS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |