Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.51 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | KIF5B | P33176 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 4/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.44 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.39 |
| ▸ | BRAF | P15056 | 2/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26102254 | 1.00 | PDK1 (0.51) | PDK1RETKIF5BKDRFLT1 | |
| SCHEMBL26100658 | 0.91 | EGFR (0.45) | PDK1KDRKITPSEN1PPARD | |
| SCHEMBL26099737 | 0.84 | BRAF (0.46) | KDRFLT1KITBRAFRAF1 | |
| SCHEMBL26100111 | 0.84 | EGFR (0.47) | PDK1KDRKITPSEN1PPARD | |
| SCHEMBL26102835 | 0.84 | KIT (0.43) | KDRFLT1KITBRAFENPP1 | |
| SCHEMBL30394282 | 0.84 | KIT (0.43) | KDRFLT1KITBRAFENPP1 | |
| SCHEMBL30394324 | 0.83 | PDK1 (0.50) | PDK1RETKIF5BKDRFLT1 | |
| SCHEMBL26536178 | 0.83 | PDK1 (0.50) | PDK1RETKIF5BKDRFLT1 | |
| SCHEMBL30393909 | 0.83 | PDK1 (0.50) | PDK1RETKIF5BKDRFLT1 | |
| SCHEMBL26100249 | 0.83 | PDK1 (0.50) | PDK1RETKIF5BKDRFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | claimed |