SCHEMBL26101545

SCHEMBL26101545

CC1(C)OB(c2cn(COCC[Si](C)(C)C)nc2Br)OC1(C)C

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.34
FFAR1 O14842 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16608469 0.87 FFAR1 (0.32) DGAT1FFAR1
SCHEMBL24615233 0.85 FFAR1 (0.31) FFAR1
SCHEMBL16608570 0.85 FFAR1 (0.31) FFAR1
SCHEMBL30976695 0.82
SCHEMBL19626238 0.81 DGAT1 (0.34) DGAT1FFAR1
SCHEMBL16608637 0.81
SCHEMBL30976700 0.80 UCHL1 (0.34) DGAT1FFAR1
SCHEMBL19806524 0.79 LPL (0.40) DGAT1
SCHEMBL24497500 0.78 FFAR1 (0.34) DGAT1FFAR1
SCHEMBL24596317 0.78 UCHL1 (0.41) DGAT1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023076849-A1 INHIBITORS OF EPIDERMAL GROWTH FACTOR RECEPTOR ORIC PHARMACEUTICALS, INC. (US) 2023-05-04 WO disclosed