Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26101492 | 0.77 | GPR119 (0.50) | GPR119 | |
| SCHEMBL26101487 | 0.77 | GPR119 (0.50) | GPR119 | |
| SCHEMBL26101572 | 0.72 | AKR1C3 (0.39) | DRD2DRD4ALDH1A1MAPTGPR119 | |
| SCHEMBL14720297 | 0.70 | LIMK2 (0.48) | KMT2A | |
| SCHEMBL21541880 | 0.68 | SLC6A2 (0.46) | NPY5RDRD2DRD4MAPTKMT2A | |
| SCHEMBL26101920 | 0.67 | USP2 (0.39) | DRD2DRD4ALDH1A1MAPTHPGD | |
| SCHEMBL26103184 | 0.66 | SLC6A2 (0.43) | KDM4EALDH1A1MAPTHPGDMCL1 | |
| SCHEMBL26101451 | 0.66 | SLC6A2 (0.43) | KDM4EALDH1A1MAPTHPGDMCL1 | |
| SCHEMBL14720344 | 0.66 | OPRM1 (0.42) | KDM4EALDH1A1 | |
| SCHEMBL346162 | 0.66 | CHRM4 (0.43) | NPY5RDRD2DRD4CHRM4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023076161-A1 | TYK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |