Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720201 | 0.86 | HDAC1 (0.52) | — | |
| SCHEMBL14720297 | 0.85 | LIMK2 (0.48) | OPRD1 | |
| SCHEMBL14720668 | 0.82 | OPRD1 (0.39) | OPRD1 | |
| SCHEMBL14720407 | 0.75 | CHRM3 (0.39) | OPRD1KDM4E | |
| SCHEMBL14720186 | 0.75 | JAK2 (0.52) | KDM4E | |
| SCHEMBL14720449 | 0.74 | CHRM3 (0.52) | ALDH1A1 | |
| SCHEMBL14720115 | 0.74 | FASN (0.43) | KDM4EALDH1A1 | |
| SCHEMBL22220876 | 0.73 | BCHE (0.49) | OPRM1OPRD1ALDH1A1 | |
| SCHEMBL14720130 | 0.73 | CHIT1 (0.52) | KDM4EALDH1A1 | |
| SCHEMBL1934529 | 0.72 | HPGD (0.61) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013028445-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-02-28 | — | — | WO | disclosed |