SCHEMBL26103441

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20214829	0.88	NPC1 (0.47)	NPC1ALDH1A1HPGDCYP1A2HSD17B10
	SCHEMBL20654264	0.87	NPC1 (0.51)	NPC1ALDH1A1HPGDCYP1A2HSD17B10
	SCHEMBL20213983	0.82	ALDH1A1 (0.43)	NPC1ALDH1A1HPGDCYP1A2HSD17B10
	SCHEMBL5651486	0.81	CDC7 (0.59)	NPC1ALDH1A1HPGDCYP1A2HSD17B10
	SCHEMBL8236741	0.81	ALDH1A1 (0.46)	NPC1ALDH1A1HPGDCYP1A2HSD17B10
	SCHEMBL31078569	0.78	ALDH1A1 (0.44)	NPC1ALDH1A1HPGDCYP1A2HSD17B10
	SCHEMBL9199237	0.78	NPC1 (0.49)	NPC1ALDH1A1HPGDCYP1A2HSD17B10
	SCHEMBL20214190	0.78	NPC1 (0.42)	NPC1ALDH1A1HPGDCYP1A2HSD17B10
	SCHEMBL5112527	0.77	NPC1 (0.48)	NPC1ALDH1A1HPGDCYP1A2HSD17B10
	SCHEMBL31078794	0.76	ALDH1A1 (0.44)	NPC1ALDH1A1HPGDCYP1A2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.