SCHEMBL26104239

SCHEMBL26104239

NNS(=O)(=O)C1CCN(C(=O)c2ccc(O)cc2)C1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 4/20 0.45
CA12 O43570 3/20 0.43
CA1 P00915 3/20 0.43
CA2 P00918 3/20 0.43
CA7 P43166 3/20 0.43
CA9 Q16790 3/20 0.43
CA14 Q9ULX7 3/20 0.43
L3MBTL3 Q96JM7 7/20 0.42
L3MBTL1 Q9Y468 4/20 0.42
MBTD1 Q05BQ5 3/20 0.39
TP53BP1 Q12888 1/20 0.39
L3MBTL4 Q8NA19 1/20 0.39
GLA P06280 1/20 0.39
HSD17B10 Q99714 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
ATM Q13315 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25284114 0.92 MGLL (0.50) MGLLCA12CA1CA2CA7
SCHEMBL20214435 0.75
SCHEMBL23775674 0.71 MGLL (0.59) MGLLCA12CA1CA2CA7
SCHEMBL18475959 0.68 ACHE (0.72) MGLLCA12CA1CA2CA7
SCHEMBL14523155 0.68 HPGD (0.64) MGLLHSD17B10
SCHEMBL16003001 0.68 MGLL (0.55) MGLLL3MBTL3L3MBTL1MBTD1TP53BP1
SCHEMBL25873675 0.68 KMT2A (0.53)
SCHEMBL20213925 0.67 EPHX1 (0.45) CA12CA1CA2CA9
SCHEMBL20232906 0.67 EPHX1 (0.45) CA12CA1CA2CA9
SCHEMBL13314119 0.66 MGLL (0.64) MGLLL3MBTL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023074936-A1 BIFUNCTIONAL COMPOUND USING UBR BOX DOMAIN-BINDING LIGAND 주식회사 오토텍바이오 2023-05-04 WO claimed
WO-2023074936-A1 BIFUNCTIONAL COMPOUND USING UBR BOX DOMAIN-BINDING LIGAND 주식회사 오토텍바이오 2023-05-04 WO disclosed