Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | SLC9A5 | Q14940 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26108316 | 0.86 | PLAU (0.49) | GRM5ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL11469206 | 0.81 | PLAU (0.60) | GRM5ALDH1A1NPC1RAB9AMEN1 | |
| N,N-Hexamethyleneamiloride SCHEMBL29384339 | 0.80 | PLAU (0.62) | GRM5ALDH1A1NPC1RAB9AMEN1 | |
| N,N-Hexamethyleneamiloride SCHEMBL7862943 | 0.80 | PLAU (0.62) | GRM5ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL11460538 | 0.80 | PLAU (0.62) | GRM5ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL26107826 | 0.80 | GRM5 (0.48) | GRM5ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL26104614 | 0.78 | ALDH1A1 (0.47) | GRM5ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL3864653 | 0.74 | GRM5 (1.00) | GRM5ALDH1A1NPC1RAB9AMEN1 | |
| Bromide SCHEMBL8784397 | 0.73 | DRD2 (0.44) | GRM5ALDH1A1KMT2AKDM4EHPGD | |
| SCHEMBL5430135 | 0.70 | PLAU (0.66) | GRM5PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250270165-A1 | COMPOSITIONS FOR AND METHODS OF MODULATING RNA STABILITY | UNIV DUKE (US) | 2025-08-28 | — | — | US | disclosed |
| WO-2023183887-A2 | COMPOSITIONS FOR AND METHODS OF MODULATING RNA STABILITY | DUKE UNIVERSITY (US) | 2023-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250270165-A1 | COMPOSITIONS FOR AND METHODS OF MODULATING RNA STABILITY | NSUN2, NSUN3, HNRNPH1 | GRM5 4141/4885ALDH1A1 3559/4885NPC1 1087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.