Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26107399 | 0.87 | SCN9A (0.38) | PDE10A | |
| SCHEMBL26106940 | 0.85 | HTR1A (0.41) | PDE10A | |
| SCHEMBL26105526 | 0.83 | PDE10A (0.33) | PDE10A | |
| SCHEMBL26105233 | 0.81 | PDE10A (0.35) | PDE10A | |
| SCHEMBL26106177 | 0.81 | LIPE (0.41) | — | |
| SCHEMBL30591679 | 0.78 | TEAD1 (0.39) | PDE10A | |
| SCHEMBL26103340 | 0.78 | TEAD1 (0.39) | PDE10A | |
| SCHEMBL30591841 | 0.78 | PDE10A (0.38) | PDE10A | |
| SCHEMBL26105746 | 0.77 | PDE10A (0.38) | PDE10A | |
| SCHEMBL26106268 | 0.76 | SCN9A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183768-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-28 | — | — | WO | claimed |
| WO-2023183768-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-28 | — | — | WO | disclosed |