Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26106392 | 0.88 | SCN9A (0.36) | SCN9ALIPE | |
| SCHEMBL26105526 | 0.87 | PDE10A (0.33) | PDE10A | |
| SCHEMBL26105097 | 0.86 | CHRM4 (0.35) | SCN9ALIPEALOX5APFEN1 | |
| SCHEMBL26105935 | 0.86 | HTR1A (0.41) | PDE10A | |
| SCHEMBL26107399 | 0.84 | SCN9A (0.38) | SCN9APDE10ALIPE | |
| SCHEMBL26105746 | 0.84 | PDE10A (0.38) | SCN9APDE10ALIPE | |
| SCHEMBL26112177 | 0.82 | PDE10A (0.37) | SCN9APDE10ALIPEALOX5APFEN1 | |
| SCHEMBL26108503 | 0.82 | PDE10A (0.37) | SCN9APDE10A | |
| SCHEMBL31474452 | 0.81 | PDE10A (0.41) | SCN9APDE10ALIPE | |
| SCHEMBL26106343 | 0.81 | SCN9A (0.35) | SCN9APDE10ALIPEALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183768-A2 | SMALL MOLECULE INHIBITORS OF TEA DOMAIN FAMILY MEMBERS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-09-28 | — | — | WO | disclosed |