Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 2/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.39 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.37 |
| ▸ | AXL | P30530 | 2/20 | 0.37 |
| ▸ | SGK1 | O00141 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26521358 | 0.84 | KDM4E (0.46) | KDM4EALDH1A1CSF1RMAPKAPK2CAMKK2 | |
| SCHEMBL4372018 | 0.70 | HTR7 (0.47) | KDM4EALDH1A1CSNK2A1 | |
| SCHEMBL8870966 | 0.70 | CSNK2A1 (0.49) | KDM4EALDH1A1CSNK2A1 | |
| SCHEMBL4071289 | 0.67 | EGFR (0.58) | EGFRCSF1R | |
| SCHEMBL13627444 | 0.65 | PARP1 (0.36) | — | |
| SCHEMBL6638123 | 0.64 | CYP3A4 (0.60) | KDM4EALDH1A1 | |
| SCHEMBL22283252 | 0.63 | PDE3B (0.46) | ALDH1A1 | |
| SCHEMBL700288 | 0.62 | MAPT (0.62) | EGFRKDM4EALDH1A1GRIK1GRIK2 | |
| SCHEMBL3072721 | 0.61 | NOTUM (0.66) | EGFRKDM4EALDH1A1GRIK1GRIK2 | |
| Terephthalic Acid SCHEMBL9577834 | 0.60 | TSHR (0.80) | EGFRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183652-A1 | DUAL CXCR4-BTK INHIBITORS | X4 PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |