Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 14/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 14/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15707647 | 0.75 | GSK3B (0.41) | CHEK1PIM1PARP1ALDH1A1AKT1 | |
| SCHEMBL2272870 | 0.75 | PARP1 (0.39) | PDE3BPDE3ACHEK1PIM1PARP1 | |
| SCHEMBL12410480 | 0.71 | ADORA1 (0.38) | ADORA1CHEK1PIM1PARP1ALDH1A1 | |
| SCHEMBL13627444 | 0.71 | PARP1 (0.36) | CHEK1PIM1PARP1AKT1FLT3 | |
| SCHEMBL25194691 | 0.68 | SMN1; SMN2 (0.48) | CHEK1PIM1PARP1ALDH1A1AKT1 | |
| SCHEMBL5765110 | 0.67 | PARP1 (0.37) | ADORA1CHEK1PIM1PARP1AKT1 | |
| Allopurinol SCHEMBL6034419 | 0.65 | XDH (0.50) | CHEK1PIM1ALDH1A1AKT1FLT3 | |
| SCHEMBL12410487 | 0.65 | LMNA (0.50) | CHEK1ALDH1A1ALOX15SMN1; SMN2 | |
| Hypoxanthine SCHEMBL17276814 | 0.64 | ALDH1A1 (0.37) | PIM1PARP1ALDH1A1PIM3RPS6KA3 | |
| SCHEMBL12489082 | 0.63 | PIM1 (0.51) | CHEK1PIM1ALDH1A1AKT1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3689870-B1 | ANALGESIC DRUG USING PAC1 RECEPTOR ANTAGONISTIC DRUG | UNIV KAGOSHIMA (JP) | 2022-07-13 | — | — | EP | disclosed |
| US-11365194-B2 | Analgesic drug using PAC1 receptor antagonistic drug | KAGOSHIMA UNIVERSITY (JP) | 2022-06-21 | — | — | US | disclosed |
| US-20220184081-A1 | ANTIPRURITIC AGENT USING PAC1 RECEPTOR ANTAGONIST | KAGOSHIMA UNIVERSITY (JP) | 2022-06-16 | — | — | US | disclosed |
| EP-3932490-A1 | ANTIPRURITIC AGENT USING PAC1 RECEPTOR ANTAGONIST | Kagoshima University (JP) | 2022-01-05 | — | — | EP | disclosed |
| US-20210188841-A1 | ANALGESIC DRUG USING PAC1 RECEPTOR ANTAGONISTIC DRUG | KAGOSHIMA UNIVERSITY (JP) | 2021-06-24 | — | — | US | disclosed |
| EP-3689870-A1 | ANALGESIC DRUG USING PAC1 RECEPTOR ANTAGONISTIC DRUG | Kagoshima University (JP) | 2020-08-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188841-A1 | ANALGESIC DRUG USING PAC1 RECEPTOR ANTAGONISTIC DRUG | OPRL1, OPRK1, OPRM1 | PDE3B 2600/4885PDE3A 2204/4885ADORA1 47/4885 |
| US-20220184081-A1 | ANTIPRURITIC AGENT USING PAC1 RECEPTOR ANTAGONIST | OPRL1, OPRK1, VIPR1 | PDE3B 1617/4885PDE3A 1196/4885ADORA1 78/4885 |
| US-11365194-B2 | Analgesic drug using PAC1 receptor antagonistic drug | OPRL1, OPRK1, OPRM1 | PDE3B 2600/4885PDE3A 2204/4885ADORA1 47/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.