Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 2/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398420 | 0.85 | TUBB1 (0.49) | TUBB1ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL20730189 | 0.83 | ERN1 (0.48) | TUBB1ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL19521917 | 0.83 | KDM4E (0.64) | TUBB1ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL29119944 | 0.83 | TUBB1 (0.48) | TUBB1ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL26107883 | 0.83 | APP (0.44) | TUBB1ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL8323669 | 0.82 | PPARG (0.48) | TUBB1ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL29951235 | 0.81 | ALDH1A1 (0.52) | TUBB1ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL9681414 | 0.81 | ALDH1A1 (0.52) | TUBB1ALDH1A1TSHRKDM4ETDP1 | |
| SCHEMBL29988598 | 0.81 | CDK1 (0.61) | TUBB1ALDH1A1TSHRTDP1ERN1 | |
| SCHEMBL13925375 | 0.81 | POLB (0.66) | TUBB1ALDH1A1TSHRKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250214951-A1 | 3-PHENYLISOXAZOLE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING EYE DISEASE, CONTAINING SAME AS ACTIVE INGREDIENT | VASTHERA CO., LTD. (KR) | 2025-07-03 | — | — | US | disclosed |
| CN-119095831-A | 3-Phenylisoxazole derivatives and pharmaceutical compositions for preventing or treating eye diseases containing the same as active ingredient | 瓦斯塞拉股份有限公司 | 2024-12-06 | — | — | CN | disclosed |
| WO-2023182871-A1 | 3-PHENYLISOXAZOLE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING EYE DISEASE, CONTAINING SAME AS ACTIVE INGREDIENT | 바스테라 주식회사 | 2023-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250214951-A1 | 3-PHENYLISOXAZOLE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING EYE DISEASE, CONTAINING SAME AS ACTIVE INGREDIENT | ATG7, BECN1, MAP1LC3B | TUBB1 1190/4885ALDH1A1 336/4885TSHR 2357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.