Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26109533 | 0.92 | KIT (0.35) | PIK3CDFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL26108721 | 0.86 | KCNH2 (0.33) | BTK | |
| SCHEMBL30582505 | 0.86 | BTK (0.41) | PIK3CDBTKFGFR1FGFR2FGFR4 | |
| SCHEMBL26109846 | 0.86 | KCNH2 (0.36) | BTK | |
| SCHEMBL26109178 | 0.85 | FGFR1 (0.31) | FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL26108434 | 0.85 | KCNH2 (0.30) | — | |
| SCHEMBL26108662 | 0.84 | FLT3 (0.34) | BTK | |
| SCHEMBL26109064 | 0.84 | FLT3 (0.34) | BTK | |
| SCHEMBL26109006 | 0.83 | RIPK2 (0.35) | PIK3CDFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL26108781 | 0.83 | BTK (0.35) | BTKFGFR1FGFR2FGFR4FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | claimed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |