Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.55 |
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.54 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ADK | P55263 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 4/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | HCK | P08631 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30582626 | 1.00 | DYRK1A (0.55) | DYRK1ALRRK2CDK1CCNB1CCNA2 | |
| SCHEMBL18642946 | 0.78 | RET (0.61) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL7701563 | 0.74 | KDM4E (0.47) | LRRK2CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL7696404 | 0.74 | ADORA2A (0.54) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL15233798 | 0.73 | CDK1 (0.74) | LRRK2CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL7699720 | 0.72 | CDK1 (0.46) | LRRK2CDK1CCNB1CCNA2CDK2 | |
| SCHEMBL30582621 | 0.71 | DYRK1A (1.00) | DYRK1ALRRK2CCNA2CDK2CCNA1 | |
| SCHEMBL26110102 | 0.71 | DYRK1A (1.00) | DYRK1ALRRK2CCNA2CDK2CCNA1 | |
| SCHEMBL15233797 | 0.70 | CCNA2 (0.74) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL18656762 | 0.69 | DYRK1A (0.58) | DYRK1ALRRK2ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024091370-A1 | 5,6-FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2024-05-02 | — | — | WO | disclosed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2023192502-A1 | SPIROBICYCLIC COMPOUNDS | ACERAND THERAPEUTICS (USA) LIMITED (US) | 2023-10-05 | — | — | WO | disclosed |