Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.45 |
| ▸ | RPS6KA3 | P51812 | 5/20 | 0.44 |
| ▸ | FYN | P06241 | 2/20 | 0.44 |
| ▸ | VCP | P55072 | 2/20 | 0.44 |
| ▸ | YES1 | P07947 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 4/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699720 | 0.89 | CDK1 (0.46) | KDM4EMAPK1TSHRHTTHSD17B10 | |
| SCHEMBL8991251 | 0.79 | KDM4E (0.49) | KDM4EMAPK1TSHRHTTHSD17B10 | |
| SCHEMBL7702669 | 0.78 | DYRK1A (0.57) | KDM4EMAPK1TSHRHTTHSD17B10 | |
| SCHEMBL7696404 | 0.77 | ADORA2A (0.54) | KDM4EMAPK1TSHRHTTHSD17B10 | |
| SCHEMBL8991261 | 0.76 | KDM4E (0.49) | KDM4EMAPK1TSHRHTTHSD17B10 | |
| SCHEMBL30582626 | 0.74 | DYRK1A (0.55) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL7695931 | 0.74 | ADK (0.46) | KDM4EMAPK1TSHRHTTHSD17B10 | |
| SCHEMBL8990998 | 0.70 | LRRK2 (0.56) | KDM4EMAPK1TSHRHTTHSD17B10 | |
| SCHEMBL7698505 | 0.69 | FYN (0.39) | KDM4EMAPK1TSHRHTTHSD17B10 | |
| SCHEMBL8991031 | 0.69 | KDM4E (0.41) | KDM4EMAPK1TSHRHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |