Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701563 | 0.89 | KDM4E (0.47) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL7696404 | 0.78 | ADORA2A (0.54) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL7699589 | 0.77 | DYRK1A (0.55) | CCNA2CDK2CCNA1MAPK1TSHR | |
| SCHEMBL30582626 | 0.72 | DYRK1A (0.55) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL7696350 | 0.69 | LRRK2 (0.53) | MAPK1TSHRHTTKDM4EHSD17B10 | |
| SCHEMBL8991414 | 0.69 | KDM4E (0.57) | CDK1MAPK1TSHRHTTKDM4E | |
| SCHEMBL7695781 | 0.68 | DYRK1A (0.56) | CCNA2CDK2CCNA1MAPK1TSHR | |
| SCHEMBL8991251 | 0.68 | KDM4E (0.49) | MAPK1TSHRHTTKDM4EHSD17B10 | |
| SCHEMBL8991048 | 0.67 | KDM4E (0.57) | CDK1MAPK1TSHRHTTKDM4E | |
| SCHEMBL18642946 | 0.67 | RET (0.61) | CDK1CCNB1CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |