Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | FBP1 | P09467 | 8/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696582 | 0.78 | DYRK1A (0.57) | ADORA2AADORA1MEN1KMT2AFBP1 | |
| SCHEMBL7699720 | 0.78 | CDK1 (0.46) | ADORA2AADORA1MEN1KMT2ACDK1 | |
| SCHEMBL7701563 | 0.77 | KDM4E (0.47) | ADORA2AADORA1CDK1CCNB1CCNA2 | |
| SCHEMBL30582626 | 0.74 | DYRK1A (0.55) | ADORA2AADORA1CDK1CCNB1CCNA2 | |
| SCHEMBL7701013 | 0.74 | ADORA2A (0.53) | ADORA2AADORA1MEN1KMT2AFBP1 | |
| SCHEMBL7701581 | 0.71 | DYRK1A (0.55) | ADORA2AADORA1MEN1KMT2AKDM4E | |
| SCHEMBL5364361 | 0.70 | ADORA2A (1.00) | ADORA2AADORA1FBP1 | |
| SCHEMBL7701585 | 0.70 | ADRA1D (0.48) | ADORA2AADORA1FBP1CDK1PIK3CD | |
| SCHEMBL7701507 | 0.69 | ADORA2A (0.50) | ADORA2AADORA1FBP1CDK1KDM4E | |
| SCHEMBL8991414 | 0.68 | KDM4E (0.57) | ADORA2AADORA1MEN1KMT2AFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |