SCHEMBL26109732

SCHEMBL26109732

CC(C)(C)[Si](C)(C)OC[C@H]1O[C@@H](n2cnc3c(NC(=O)c4ccccc4)ncnc32)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1OCCC#N

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ PRMT6 Q96LA8 1/20 0.45
▸ P2RY12 Q9H244 6/20 0.42
▸ ADORA1 P30542 3/20 0.41
▸ P2RY2 P41231 1/20 0.41
▸ P2RY1 P47900 1/20 0.41
▸ P2RY6 Q15077 1/20 0.41
▸ BMPR1B O00238 1/20 0.40
▸ PRKAB2 O43741 1/20 0.40
▸ PRKAG1 P54619 1/20 0.40
▸ PRKAA2 P54646 1/20 0.40
▸ PRKAA1 Q13131 1/20 0.40
▸ PRKAG3 Q9UGI9 1/20 0.40
▸ PRKAG2 Q9UGJ0 1/20 0.40
▸ PRKAB1 Q9Y478 1/20 0.40
▸ DNPH1 O43598 1/20 0.40
▸ P2RX3 P56373 1/20 0.39
▸ P2RX4 Q99571 1/20 0.39
▸ P2RX2 Q9UBL9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22206844 0.91 PRMT6 (0.50) PRMT6P2RY12ADORA1P2RY2P2RY1
SCHEMBL26109827 0.91 PRMT6 (0.47) PRMT6P2RY12ADORA1P2RY2P2RY1
SCHEMBL26109806 0.90 PRMT6 (0.47) PRMT6P2RY12ADORA1P2RY2P2RY1
SCHEMBL26109581 0.90 PRMT6 (0.46) PRMT6P2RY12ADORA1P2RY2P2RY1
SCHEMBL26112399 0.89 PRMT6 (0.48) PRMT6P2RY12ADORA1P2RY2P2RY1
SCHEMBL26106020 0.89 PRMT6 (0.46) PRMT6P2RY12ADORA1P2RY2P2RY1
SCHEMBL26107926 0.88 PRMT6 (0.46) PRMT6P2RY12ADORA1P2RY2P2RY1
SCHEMBL26113232 0.88 PRMT6 (0.47) PRMT6P2RY12ADORA1P2RY2P2RY1
SCHEMBL30586895 0.88 PRMT6 (0.57) PRMT6P2RY12ADORA1P2RY2P2RY1
SCHEMBL26110467 0.87 PRMT6 (0.46) PRMT6P2RY12ADORA1P2RY2P2RY1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250207163-A1 METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACIDS TRILINK BIOTECHNOLOGIES, LLC 2025-06-26 — — US disclosed
EP-4499824-A1 METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACIDS Molecular Assemblies, Inc. (US) 2025-02-05 — — EP disclosed
WO-2023183569-A1 METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACIDS Molecular Assemblies, Inc. (US) 2023-09-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250207163-A1 METHODS AND APPARATUS FOR SYNTHESIZING NUCLEIC ACIDS RNGTT, POLRMT, POLN PRMT6 2509/4885P2RY12 3422/4885ADORA1 2763/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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