Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.56 |
| ▸ | KMO | O15229 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15449693 | 0.84 | GPR35 (0.40) | GPR35KMOKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL17440068 | 0.79 | NQO2 (0.48) | KDM4EL3MBTL1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL2342735 | 0.79 | GPR35 (0.50) | GPR35KMOTSHRALOX15HIF1A | |
| SCHEMBL29556178 | 0.79 | GPR35 (0.50) | GPR35KMOTSHRALOX15HIF1A | |
| SCHEMBL15449707 | 0.74 | KMO (0.48) | GPR35KMOKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28367544 | 0.72 | GPR35 (0.44) | GPR35KMOTSHRALOX15HIF1A | |
| SCHEMBL12641092 | 0.71 | ALOX15 (0.46) | GPR35KMOTSHRALOX15HIF1A | |
| SCHEMBL15439882 | 0.71 | PIK3CA (0.48) | GPR35KMOTSHRALOX15KDM4E | |
| SCHEMBL16701192 | 0.70 | HCAR2 (0.47) | GPR35TSHRALOX15HIF1AKDM4E | |
| SCHEMBL23884906 | 0.69 | ALOX15 (0.45) | GPR35TSHRALOX15HIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023193760-A1 | COMPOUNDS AND METHODS OF TREATING CANCERS | CULLGEN (SHANGHAI) , INC. (CN) | 2023-10-12 | — | — | WO | disclosed |