Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 2/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26115023 | 1.00 | SMN1; SMN2 (0.33) | SMN1; SMN2ALDH1A1HTTTSHRMETAP2 | |
| SCHEMBL16634840 | 0.77 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1METAP2P2RX7KMT2A | |
| SCHEMBL26116791 | 0.75 | MMP2 (0.38) | SMN1; SMN2ALDH1A1HTTMETAP2POLB | |
| SCHEMBL26116787 | 0.75 | MMP2 (0.38) | SMN1; SMN2ALDH1A1HTTMETAP2POLB | |
| SCHEMBL25366035 | 0.70 | F2 (0.45) | SMN1; SMN2ALDH1A1HTTADAM17TDP1 | |
| SCHEMBL25366044 | 0.70 | F2 (0.45) | SMN1; SMN2ALDH1A1HTTADAM17TDP1 | |
| SCHEMBL15240887 | 0.70 | LMNA (0.43) | SMN1; SMN2ALDH1A1HTTTSHRMETAP2 | |
| SCHEMBL1250785 | 0.64 | MMP2 (0.36) | POLBTDP1 | |
| SCHEMBL6921106 | 0.64 | MMP2 (0.36) | POLBTDP1 | |
| SCHEMBL2576147 | 0.64 | MMP2 (0.36) | POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023183405-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2023-09-28 | — | — | WO | disclosed |