SCHEMBL26115115

SCHEMBL26115115

COCCOCCOCCNC(=O)Cc1csc(C)n1

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.51
▸ SMN1; SMN2 Q16637 6/20 0.49
▸ NPC1 O15118 4/20 0.47
▸ RAB9A P51151 4/20 0.47
▸ TP53 P04637 2/20 0.46
▸ MEN1 O00255 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ GAA P10253 2/20 0.46
▸ HTT P42858 1/20 0.46
▸ ALDH1A1 P00352 3/20 0.45
▸ HPGD P15428 1/20 0.45
▸ KDM4E B2RXH2 3/20 0.43
▸ GLA P06280 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ SLC12A2 P55011 1/20 0.43
▸ SLC12A5 Q9H2X9 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26113589 0.87 ALDH1A1 (0.56) MAPTSMN1; SMN2NPC1RAB9ATP53
SCHEMBL9709994 0.73 SMN1; SMN2 (0.54) MAPTSMN1; SMN2NPC1RAB9ATP53
SCHEMBL26334694 0.71 SMN1; SMN2 (0.56) MAPTSMN1; SMN2NPC1RAB9ATP53
SCHEMBL9331152 0.70 HIF1A (0.58) MAPTSMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL22051693 0.70 GAA (0.59) MAPTSMN1; SMN2NPC1RAB9ATP53
SCHEMBL3614972 0.69 PKM (0.57) MAPTMEN1KMT2AGAAALDH1A1
SCHEMBL16770017 0.69 SMN1; SMN2 (0.57) MAPTSMN1; SMN2NPC1RAB9ATP53
SCHEMBL15259129 0.67 MEN1 (0.50) SMN1; SMN2MEN1KMT2AHTTALDH1A1
SCHEMBL12081798 0.67 TSHR (0.55) SMN1; SMN2MEN1KMT2AHTTALDH1A1
SCHEMBL7795327 0.67 SMN1; SMN2 (0.58) MAPTSMN1; SMN2NPC1RAB9ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333782-A1 COMPOSITIONS INCLUDING AQUEOUS AMINE BORANE COMPLEXES AND POLYNUCLEOTIDES, AND METHODS OF USING THE SAME TO DETECT METHYLCYTOSINE OR HYDROXYMETHYLCYTOSINE ILLUMINA INC (US) 2025-10-30 — — US disclosed
EP-4499859-A1 COMPOSITIONS INCLUDING AQUEOUS AMINE BORANE COMPLEXES AND POLYNUCLEOTIDES, AND METHODS OF USING THE SAME TO DETECT METHYLCYTOSINE OR HYDROXYMETHYLCYTOSINE Illumina, Inc. (US) 2025-02-05 — — EP disclosed
WO-2023187012-A1 COMPOSITIONS INCLUDING AQUEOUS AMINE BORANE COMPLEXES AND POLYNUCLEOTIDES, AND METHODS OF USING THE SAME TO DETECT METHYLCYTOSINE OR HYDROXYMETHYLCYTOSINE ILLUMINA CAMBRIDGE LIMITED (GB) 2023-10-05 — — WO disclosed
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