Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26433080 | 0.91 | LMNA (0.58) | LMNAMEN1KMT2ACYP1A2NR1I2 | |
| SCHEMBL30596372 | 0.91 | LMNA (0.58) | LMNAMEN1KMT2ACYP1A2NR1I2 | |
| SCHEMBL26110486 | 0.86 | LMNA (0.47) | LMNAMEN1KMT2ACYP1A2NR1I2 | |
| SCHEMBL6235584 | 0.82 | LMNA (0.62) | LMNAMEN1KMT2ACYP1A2NR1I2 | |
| SCHEMBL5200654 | 0.81 | LMNA (0.52) | LMNAMEN1KMT2ACYP1A2NR1I2 | |
| SCHEMBL5348039 | 0.80 | LMNA (0.51) | LMNAMEN1KMT2ACYP1A2NR1I2 | |
| SCHEMBL25367964 | 0.78 | LMNA (0.48) | LMNAMEN1KMT2ACYP1A2NR1I2 | |
| SCHEMBL30596373 | 0.77 | LMNA (0.57) | LMNAMEN1KMT2ACYP1A2NR1I2 | |
| SCHEMBL26433353 | 0.77 | LMNA (0.57) | LMNAMEN1KMT2ACYP1A2NR1I2 | |
| SCHEMBL25367915 | 0.77 | LMNA (0.47) | LMNAMEN1KMT2ACYP1A2NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023191536-A1 | THIOBENZIMIDAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF | 고려대학교 산학협력단 | 2023-10-05 | — | — | WO | disclosed |