Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 8/20 | 0.51 |
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5200654 | 0.91 | LMNA (0.52) | LMNAMEN1KMT2ANR1I2CYP1A2 | |
| SCHEMBL5348039 | 0.90 | LMNA (0.51) | LMNAMEN1KMT2ANR1I2CYP1A2 | |
| SCHEMBL11359812 | 0.89 | LMNA (0.77) | LMNAMEN1KMT2ANR1I2CYP1A2 | |
| Fenbendazole SCHEMBL3988034 | 0.87 | LMNA (0.82) | LMNAMEN1KMT2ANR1I2CYP1A2 | |
| Fenbendazole SCHEMBL31547342 | 0.87 | LMNA (0.82) | LMNAMEN1KMT2ANR1I2CYP1A2 | |
| Fenbendazole SCHEMBL166352 | 0.87 | LMNA (0.82) | LMNAMEN1KMT2ANR1I2CYP1A2 | |
| Fenbendazole SCHEMBL31547327 | 0.87 | LMNA (0.82) | LMNAMEN1KMT2ANR1I2CYP1A2 | |
| Fenbendazole SCHEMBL28228589 | 0.86 | LMNA (0.80) | LMNAMEN1KMT2ANR1I2CYP1A2 | |
| Fenbendazole SCHEMBL9639071 | 0.86 | LMNA (0.80) | LMNAMEN1KMT2ANR1I2CYP1A2 | |
| SCHEMBL25367915 | 0.86 | LMNA (0.47) | LMNAMEN1KMT2ANR1I2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0084516-B1 | ANTHELMINTICS | CIBA-GEIGY AG (CH) | 1985-12-04 | — | — | EP | claimed |
| EP-0060810-B1 | ANTHELMINTICS | CIBA-GEIGY AG (CH) | 1984-10-17 | — | — | EP | claimed |
| EP-0896517-B1 | METHOD FOR PROMOTING HAIR, NAIL, AND SKIN KERATINIZATION | SCHICK MARY P (US) | 2005-05-25 | — | — | EP | disclosed |
| EP-0896517-A4 | METHOD FOR PROMOTING HAIR, NAIL, AND SKIN KERATINIZATION | SCHICK MARY P (US) | 2000-02-09 | — | — | EP | disclosed |
| EP-0896517-A1 | METHOD FOR PROMOTING HAIR, NAIL, AND SKIN KERATINIZATION | Schick, Mary P. (US) | 1999-02-17 | — | — | EP | disclosed |
| WO-1997035540-A1 | METHOD FOR PROMOTING HAIR, NAIL, AND SKIN KERATINIZATION | SCHICK MARY P (US) | 1997-10-02 | — | — | WO | disclosed |
| EP-0107963-B1 | INDOLE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-04-01 | — | — | EP | disclosed |
| EP-0107963-A1 | Indole derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-05-09 | — | — | EP | disclosed |
| EP-0090368-A1 | Anthelmintic preparations | HOECHST UK LIMITED (GB) | 1983-10-05 | — | — | EP | disclosed |
| US-4076827-A | Method of treating helminthiasis by parenteral administration of sulfoxide derivatives of benzimidazoles | E. R. SQUIBB & SONS, INC. (US) | 1978-02-28 | — | — | US | disclosed |