Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.32 |
| ▸ | DRD3 | P35462 | 6/20 | 0.32 |
| ▸ | HTR1D | P28221 | 3/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 3/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | DRD5 | P21918 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
| ▸ | HTR5A | P47898 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4016506 | 1.00 | DRD2 (0.32) | DRD2DRD3HTR1DCES2DRD4 | |
| SCHEMBL2221698 | 0.88 | CES2 (0.36) | DRD2DRD3HTR1DCES2DRD4 | |
| SCHEMBL29178381 | 0.84 | CES2 (0.31) | CES2 | |
| SCHEMBL18392904 | 0.84 | CES2 (0.33) | DRD2DRD3HTR1DCES2DRD4 | |
| SCHEMBL13132554 | 0.83 | DRD2 (0.33) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL4596459 | 0.83 | DRD2 (0.35) | DRD2DRD3HTR1DCES2DRD4 | |
| SCHEMBL5234275 | 0.81 | DRD2 (0.34) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL8291680 | 0.81 | DRD2 (0.32) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL17802127 | 0.80 | AKR1C3 (0.35) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL1302897 | 0.78 | DRD2 (0.33) | DRD2DRD3HTR1DDRD4DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4496789-A1 | TEAD INHIBITORS AND METHODS OF USE | Sporos Biodiscovery, Inc. (US) | 2025-01-29 | — | — | EP | disclosed |
| WO-2023183437-A1 | TEAD INHIBITORS AND METHODS OF USE | SPOROS BIODISCOVERY, INC. (US) | 2023-09-28 | — | — | WO | disclosed |