SCHEMBL29178381

SCHEMBL29178381

CS(=O)(=O)OC1=CCC(C(F)(F)F)CC1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4016506 0.84 DRD2 (0.32) CES2
SCHEMBL6360983 0.78 LMNA (0.35) CES2LMNA
SCHEMBL2221698 0.75 CES2 (0.36) CES2LMNA
SCHEMBL18392904 0.72 CES2 (0.33) CES2LMNA
SCHEMBL4596459 0.71 DRD2 (0.35) CES2
SCHEMBL5234275 0.68 DRD2 (0.34)
SCHEMBL13248079 0.67 LMNA (0.62) CES2LMNA
SCHEMBL13132554 0.67 DRD2 (0.33)
SCHEMBL12987755 0.67
SCHEMBL16494063 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117561058-A CDK2 inhibitors and methods of use thereof 塞迪拉治疗股份有限公司 2024-02-13 CN disclosed