Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | IDH1 | O75874 | 1/20 | 0.46 |
| ▸ | IDH2 | P48735 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 6/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.45 |
| ▸ | CDK2 | P24941 | 4/20 | 0.45 |
| ▸ | JUN | P05412 | 4/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30603249 | 1.00 | ADORA2A (0.47) | ADORA2AIDH1IDH2ALDH1A1MAPK9 | |
| SCHEMBL26506937 | 0.86 | GRIN2B (0.47) | GPR119 | |
| SCHEMBL26507050 | 0.83 | PCSK9 (0.42) | MAPK9MAPK8CDK2MAPK10MAPK1 | |
| SCHEMBL26507191 | 0.83 | PCSK9 (0.42) | MAPK9MAPK8CDK2MAPK10MAPK1 | |
| SCHEMBL26114178 | 0.82 | PCSK9 (0.41) | GPR119USP30 | |
| SCHEMBL14190733 | 0.79 | ALDH1A1 (0.55) | ADORA2AIDH1IDH2ALDH1A1CDK2 | |
| SCHEMBL12367077 | 0.79 | ALDH1A1 (0.55) | ADORA2AIDH1IDH2ALDH1A1CDK2 | |
| SCHEMBL3650816 | 0.79 | HDAC8 (0.52) | ADORA2AIDH1IDH2ALDH1A1MAPK9 | |
| SCHEMBL26505551 | 0.78 | CDK1 (0.48) | MAPK9MAPK8CDK2MAPK10CCNA2 | |
| SCHEMBL4062890 | 0.78 | GPR119 (0.61) | ADORA2AIDH1IDH2ALDH1A1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260049086-A1 | CDK9 INHIBITORS | BAERENKRAFT THERAPEUTICS LLC (US) | 2026-02-19 | — | — | US | disclosed |
| US-12275738-B2 | CDK9 inhibitors | Biolexis Therapeutics, Inc. (US) | 2025-04-15 | — | — | US | disclosed |
| WO-2023196517-A1 | CDK9 INHIBITORS | Biolexis Therapeutics, Inc. (US) | 2023-10-12 | — | — | WO | disclosed |
| WO-2023196517-A1 | CDK9 INHIBITORS | Biolexis Therapeutics, Inc. (US) | 2023-10-12 | — | — | WO | disclosed |
| US-20230322792-A1 | CDK9 INHIBITORS | BAERENKRAFT THERAPEUTICS, LLC | 2023-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322792-A1 | CDK9 INHIBITORS | CDK9, CDK19, CDK3 | ADORA2A 3437/4885IDH1 1470/4885IDH2 2305/4885 |
| US-20260049086-A1 | CDK9 INHIBITORS | CDK9, CDK6, CDK19 | ADORA2A 3800/4885IDH1 1033/4885IDH2 1915/4885 |
| US-12275738-B2 | CDK9 inhibitors | CDK9, CDK19, CDK3 | ADORA2A 3437/4885IDH1 1470/4885IDH2 2305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.