Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4283725 | 0.82 | CYP1A2 (0.53) | MEN1KMT2ALMNAHTTMAPT | |
| SCHEMBL17009732 | 0.82 | CYP1A2 (0.53) | MEN1KMT2ALMNAHTTMAPT | |
| SCHEMBL3093455 | 0.81 | MAPK1 (0.47) | MAOAMAOBMEN1KMT2ALMNA | |
| SCHEMBL9651648 | 0.80 | MAOA (0.59) | MAOAMAOBMEN1KMT2ALMNA | |
| SCHEMBL26125375 | 0.80 | MAOA (0.60) | MAOAMEN1KMT2ALMNAHTT | |
| SCHEMBL8945818 | 0.79 | MAOA (0.59) | MAOAMAOBMEN1KMT2ALMNA | |
| SCHEMBL26125591 | 0.77 | ATM (0.41) | MEN1KMT2ALMNAHTTMAPT | |
| SCHEMBL15289503 | 0.77 | ATM (0.41) | MEN1KMT2ALMNAHTTMAPT | |
| SCHEMBL26122944 | 0.76 | RAB9A (0.44) | MAOAMAOBMEN1KMT2AMAPT | |
| SCHEMBL19329494 | 0.75 | CYP1A2 (0.70) | MAOAMAOBMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023186881-A1 | P38 MAP KINASE INHIBITORS FOR USE IN THE TREATMENT OF COLORECTAL CANCER | BADEN-WÜRTTEMBERG STIFTUNG GGMBH (DE) | 2023-10-05 | — | — | WO | disclosed |
| WO-2023186881-A1 | P38 MAP KINASE INHIBITORS FOR USE IN THE TREATMENT OF COLORECTAL CANCER | BADEN-WÜRTTEMBERG STIFTUNG GGMBH (DE) | 2023-10-05 | — | — | WO | disclosed |