Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30632968 | 0.86 | ALDH1A1 (0.72) | ALDH1A1POLBCYP2C9SMN1; SMN2CYP2D6 | |
| SCHEMBL26123763 | 0.86 | ALDH1A1 (0.67) | ALDH1A1POLBCYP2C9SMN1; SMN2CYP2D6 | |
| SCHEMBL28864240 | 0.84 | ALDH1A1 (0.76) | ALDH1A1POLBCYP2C9SMN1; SMN2CYP2D6 | |
| SCHEMBL8468215 | 0.82 | GAA (0.63) | ALDH1A1POLBSMN1; SMN2CYP2D6TSHR | |
| SCHEMBL28864238 | 0.81 | ALDH1A1 (0.51) | ALDH1A1POLBCYP2C9SMN1; SMN2CYP2D6 | |
| SCHEMBL1652022 | 0.81 | FNTA (0.46) | ALDH1A1POLBCYP2C9SMN1; SMN2CYP2D6 | |
| SCHEMBL30480290 | 0.79 | ALDH1A1 (0.47) | ALDH1A1POLBCYP2C9SMN1; SMN2CYP2D6 | |
| SCHEMBL8747161 | 0.75 | ALDH1A1 (0.79) | ALDH1A1POLBCYP2C9SMN1; SMN2TSHR | |
| SCHEMBL28475041 | 0.75 | ROCK1 (0.53) | ALDH1A1POLBCYP2C9SMN1; SMN2CYP2D6 | |
| SCHEMBL28470151 | 0.74 | CYP3A4 (0.54) | ALDH1A1POLBCYP2C9SMN1; SMN2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140903-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039118-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |