SCHEMBL26124111

SCHEMBL26124111

CCOC(=O)C(C#N)NO.[U]

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
TSHR P16473 1/20 0.38
GAA P10253 2/20 0.38
MGAM O43451 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
MMP8 P22894 2/20 0.38
KMT2A Q03164 4/20 0.37
MEN1 O00255 3/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HTT P42858 2/20 0.36
LMNA P02545 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
HSD17B10 Q99714 1/20 0.34
ALOX15 P16050 1/20 0.33
MAPT P10636 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
CYP2C9 P11712 1/20 0.33
SOAT1 P35610 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20838333 0.98 ALDH1A1 (0.39) ALDH1A1TSHRGAAMGAMSI
Urea SCHEMBL31702546 0.88 MMP8 (0.36) ALDH1A1TSHRGAAMGAMSI
SCHEMBL7601775 0.82 ALDH1A1 (0.39) ALDH1A1TSHRGAAMGAMSI
SCHEMBL28440232 0.82 ALDH1A1 (0.39) ALDH1A1TSHRGAAMGAMSI
SCHEMBL1564967 0.78 SOAT1 (0.41) ALDH1A1TSHRGAAMGAMSI
SCHEMBL1194168 0.78 SOAT1 (0.41) ALDH1A1TSHRGAAMGAMSI
SCHEMBL1968575 0.77 RXFP1 (0.39) ALDH1A1TSHRGAAMGAMSI
SCHEMBL2775866 0.77 RXFP1 (0.39) ALDH1A1TSHRGAAMGAMSI
SCHEMBL2235900 0.77 ALDH1A1 (0.36) ALDH1A1TSHRGAAMGAMSI
SCHEMBL1178902 0.77 ALDH1A1 (0.36) ALDH1A1TSHRGAAMGAMSI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230381718-A1 BARRIERS INCLUDING MOLECULES COVALENTLY BONDED TO AMPHIPHILIC MOLECULES, AND METHODS OF MAKING THE SAME ILLUMINA CAMBRIDGE LIMITED (GB) 2023-11-30 US disclosed
WO-2023187112-A1 AMPHIPHILIC BLOCK-CO-POLYMERS CROSS-LINKED WITH DIFFERENT CROSS-LINKERS CONSECUTIVELY FORMING A CROSS-LINKING HIERARCHY ILLUMINA CAMBRIDGE LIMITED (GB) 2023-10-05 WO disclosed