Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 9/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26124386 | 1.00 | P2RX7 (0.59) | P2RX7KMT2ATHRBALOX12DPP4 | |
| SCHEMBL26123844 | 0.88 | P2RX7 (0.63) | P2RX7KMT2ADPP4MEN1CYP2D6 | |
| SCHEMBL26123848 | 0.88 | P2RX7 (0.63) | P2RX7KMT2ADPP4MEN1CYP2D6 | |
| SCHEMBL26124728 | 0.88 | P2RX7 (0.63) | P2RX7KMT2ADPP4MEN1CYP2D6 | |
| SCHEMBL9538607 | 0.88 | ALDH1A1 (0.52) | P2RX7KMT2AALDH1A1ACE | |
| SCHEMBL30546740 | 0.86 | P2RX7 (0.61) | P2RX7DPP4ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL30546762 | 0.86 | P2RX7 (0.61) | P2RX7DPP4ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL30546732 | 0.81 | SMN1; SMN2 (0.65) | P2RX7KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL26121213 | 0.81 | SMN1; SMN2 (0.65) | P2RX7KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL26121211 | 0.81 | SMN1; SMN2 (0.65) | P2RX7KMT2AMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250188032-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND USES THEREOF | BNH RESEARCH CO., LTD. (KR) | 2025-06-12 | — | — | US | disclosed |
| EP-4501910-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND USES THEREOF | BNH Research Co., Ltd. (KR) | 2025-02-05 | — | — | EP | disclosed |
| CN-119255981-A | Nitrogen-containing heterocyclic compound and use thereof | BNH研究有限责任公司 | 2025-01-03 | — | — | CN | disclosed |
| WO-2023191468-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND USES THEREOF | 주식회사 비엔에이치리서치 | 2023-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250188032-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND USES THEREOF | NLN, GRIN1, GRIN2A | P2RX7 424/4885KMT2A 687/4885THRB 4086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.