Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26124386 | 0.88 | P2RX7 (0.59) | ALDH1A1KMT2AP2RX7ACE | |
| SCHEMBL26124183 | 0.88 | P2RX7 (0.59) | ALDH1A1KMT2AP2RX7ACE | |
| SCHEMBL9727271 | 0.85 | ALDH1A1 (0.61) | ALDH1A1KMT2ASIGMAR1P2RX7 | |
| SCHEMBL5741063 | 0.81 | HPGD (0.63) | ALDH1A1ACE | |
| SCHEMBL5741058 | 0.81 | HPGD (0.63) | ALDH1A1ACE | |
| SCHEMBL9727236 | 0.80 | TSHR (0.57) | ALDH1A1KMT2ASIGMAR1P2RX7 | |
| SCHEMBL14959833 | 0.79 | POLB (0.63) | ALDH1A1KMT2ASIGMAR1 | |
| SCHEMBL1820777 | 0.79 | CYP1A2 (0.55) | ALDH1A1EPHX2P2RX7 | |
| SCHEMBL2032215 | 0.79 | CYP1A2 (0.55) | ALDH1A1EPHX2P2RX7 | |
| SCHEMBL2473759 | 0.79 | ALDH1A1 (0.52) | ALDH1A1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355599-B1 | 3-ARYL-PYRROLIDINE-2,4-DIONES | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| US-5142065-A | Intermediates for herbicides, fungicides, miticides and insecticides | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-25 | — | — | US | disclosed |
| US-5091537-A | Acylamino acid ester derivatives; insecticide, fungicide, herbicide, acaricide, and antimycotic agent | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |
| US-4985063-A | INSECTICIDES, MITICIDES, HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-15 | — | — | US | disclosed |
| EP-0355599-A1 | 3-Aryl-pyrrolidine-2,4-diones | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |