Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.51 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.51 |
| ▸ | MAT2A | P31153 | 17/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30608076 | 1.00 | MAPK8 (0.51) | MAPK8MAPK9MAT2APRMT5KDM4E | |
| SCHEMBL26125920 | 0.87 | MAPK8 (0.49) | MAPK8MAPK9MAT2APRMT5KDM4E | |
| SCHEMBL30608069 | 0.87 | MAPK8 (0.49) | MAPK8MAPK9MAT2APRMT5KDM4E | |
| SCHEMBL30608050 | 0.87 | MAPK8 (0.49) | MAPK8MAPK9MAT2APRMT5KDM4E | |
| SCHEMBL26128344 | 0.87 | MAPK8 (0.49) | MAPK8MAPK9MAT2APRMT5KDM4E | |
| SCHEMBL8178799 | 0.86 | KDM4E (0.46) | MAPK8MAPK9KDM4ENPSR1MEN1 | |
| SCHEMBL30358964 | 0.84 | MAT2A (0.48) | MAPK8MAPK9MAT2AKDM4ENPSR1 | |
| SCHEMBL28978826 | 0.84 | MAT2A (0.48) | MAPK8MAPK9MAT2AKDM4ENPSR1 | |
| SCHEMBL13384794 | 0.80 | KDM4E (0.47) | MAT2AKDM4ENPSR1MEN1LMNA | |
| SCHEMBL30358981 | 0.79 | MAPK8 (0.42) | MAPK8MAPK9MAT2APRMT5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023185811-A1 | NOVEL HETEROCYCLIC COMPOUND | 首药控股(北京)股份有限公司 | 2023-10-05 | — | — | WO | disclosed |