Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 5/20 | 0.48 |
| ▸ | CTSK | P43235 | 4/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28978826 | 1.00 | MAT2A (0.48) | MAT2ACTSKG6PDTLR9TDP2 | |
| SCHEMBL26125895 | 0.86 | MAT2A (0.48) | MAT2ACTSKG6PDTLR9TDP2 | |
| SCHEMBL30608124 | 0.86 | MAT2A (0.48) | MAT2ACTSKG6PDTLR9TDP2 | |
| SCHEMBL28978808 | 0.86 | MAT2A (0.48) | MAT2ACTSKG6PDTLR9TDP2 | |
| SCHEMBL29417542 | 0.86 | MAT2A (0.48) | MAT2ACTSKG6PDTLR9TDP2 | |
| SCHEMBL30608076 | 0.84 | MAPK8 (0.51) | MAT2AKDM4ENPSR1MAPK8MAPK9 | |
| SCHEMBL26124606 | 0.84 | MAPK8 (0.51) | MAT2AKDM4ENPSR1MAPK8MAPK9 | |
| SCHEMBL8178799 | 0.81 | KDM4E (0.46) | ALDH1A1POLBKDM4ENPSR1MAPK8 | |
| SCHEMBL28978580 | 0.81 | MAT2A (0.41) | MAT2ACTSKALDH1A1POLBKDM4E | |
| SCHEMBL28978830 | 0.81 | CTSK (0.43) | MAT2ACTSKTDP2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115960099-A | Aromatic ring or aryl heterocyclic pyridone compound, pharmaceutical composition and application thereof | 上海凌达生物医药有限公司 | 2023-04-14 | — | — | CN | disclosed |