Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PDE9A | O76083 | 1/20 | 0.42 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26124606 | 0.86 | MAPK8 (0.51) | KDM4EL3MBTL1KMT2AMAPK8MAPK9 | |
| SCHEMBL30608076 | 0.86 | MAPK8 (0.51) | KDM4EL3MBTL1KMT2AMAPK8MAPK9 | |
| SCHEMBL13384763 | 0.84 | ALDH1A1 (0.48) | KMT2AALDH1A1NPSR1LMNAPKM | |
| SCHEMBL26127364 | 0.82 | HPGD (0.48) | KDM4EATML3MBTL1KMT2AMAPK8 | |
| SCHEMBL30608109 | 0.82 | HPGD (0.48) | KDM4EATML3MBTL1KMT2AMAPK8 | |
| SCHEMBL13384800 | 0.81 | HSD17B10 (0.48) | KDM4EL3MBTL1KMT2AMAPK1PDE9A | |
| SCHEMBL30358964 | 0.81 | MAT2A (0.48) | KDM4EKMT2AMAPK8MAPK9CYP1A2 | |
| SCHEMBL28978826 | 0.81 | MAT2A (0.48) | KDM4EKMT2AMAPK8MAPK9CYP1A2 | |
| SCHEMBL23412054 | 0.79 | ALDH1A1 (0.58) | KDM4EL3MBTL1KMT2AMAPK8MAPK1 | |
| SCHEMBL29892161 | 0.79 | ALDH1A1 (0.58) | KDM4EL3MBTL1KMT2AMAPK8MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028081-A | TREATING PEPTIC ULCERS | SSP CO., LTD. (JP) | 2000-02-22 | — | — | US | disclosed |
| EP-0900789-A2 | Substituted quinolone derivatives and pharmaceuticals containing the same | SSP Co., Ltd. (JP) | 1999-03-10 | — | — | EP | disclosed |