Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 5/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26127806 | 0.81 | SMN1; SMN2 (0.43) | PPARGPPARDPPARAUSP2CYP2C9 | |
| SCHEMBL26125332 | 0.80 | KCNH2 (0.46) | PPARGPPARDPPARAUSP2CYP2C9 | |
| SCHEMBL13168167 | 0.79 | CYP2C9 (0.39) | PPARGPPARDPPARAUSP2CYP2C9 | |
| SCHEMBL30286314 | 0.79 | PARP1 (0.44) | PPARGPPARDPPARAUSP2CYP2C9 | |
| SCHEMBL14996529 | 0.76 | CYP3A4 (0.43) | PPARGPPARDPPARAUSP2CYP2C9 | |
| SCHEMBL26128643 | 0.75 | ACACB (0.43) | PPARGPPARDPPARAHPGDTIPARP | |
| SCHEMBL29031225 | 0.74 | MEN1 (0.48) | PPARGPPARDPPARAMEN1KMT2A | |
| SCHEMBL484575 | 0.73 | USP2 (0.52) | USP2CYP2C9MEN1KMT2ACYP3A4 | |
| SCHEMBL26122829 | 0.73 | ACACB (0.43) | PPARGPPARDPPARAMEN1KMT2A | |
| SCHEMBL484867 | 0.73 | CYP11B2 (0.54) | USP2CYP2C9MAPTCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023185073-A1 | PARP7 INHIBITOR AND USE THEREOF | 诺沃斯达药业(上海)有限公司 | 2023-10-05 | — | — | WO | disclosed |