Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 5/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26122829 | 0.93 | ACACB (0.43) | ACACBKCNH2GPR119CHRM4CHRM2 | |
| SCHEMBL26124703 | 0.80 | HPGD (0.42) | ACACBKCNH2GPR119CHRM4TRPV4 | |
| SCHEMBL26125453 | 0.78 | ACACB (0.42) | ACACBCHRM2CHRM1TIPARPSLC6A9 | |
| SCHEMBL30286308 | 0.77 | ACACB (0.42) | ACACBCHRM4CHRM2CHRM1TIPARP | |
| SCHEMBL26126183 | 0.75 | PPARG (0.41) | ACACBTIPARPPPARGPPARDPPARA | |
| SCHEMBL16437811 | 0.75 | ACACB (0.53) | ACACBCHRM4CHRM2SLC6A9HDAC3 | |
| SCHEMBL30286395 | 0.74 | ACACB (0.45) | ACACBKCNH2GPR119CHRM4TRPV4 | |
| SCHEMBL24962970 | 0.73 | GPR119 (0.57) | ACACBKCNH2GPR119TRPV4CHRM2 | |
| SCHEMBL26125223 | 0.73 | HPGD (0.42) | ACACBCHRM4CHRM2TIPARPPPARG | |
| SCHEMBL26125507 | 0.71 | TIPARP (0.43) | ACACBCHRM4CHRM2CHRM1TIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023185073-A1 | PARP7 INHIBITOR AND USE THEREOF | 诺沃斯达药业(上海)有限公司 | 2023-10-05 | — | — | WO | disclosed |