SCHEMBL26129641

SCHEMBL26129641

O=c1c2cc(Cl)ccc2[nH]c2cc3c(=O)c4c(Cl)cccc4[nH]c3cc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.47
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
DYRK1A Q13627 1/20 0.43
LMNA P02545 2/20 0.43
PTGES O14684 1/20 0.42
MEN1 O00255 5/20 0.42
KMT2A Q03164 5/20 0.42
ABCG2 Q9UNQ0 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
GAA P10253 4/20 0.42
ALDH1A1 P00352 4/20 0.42
POLB P06746 2/20 0.42
KDM4E B2RXH2 2/20 0.42
GLA P06280 2/20 0.42
HTT P42858 2/20 0.42
HPGD P15428 2/20 0.42
CYP1A2 P05177 1/20 0.42
NPC1 O15118 1/20 0.42
CASP6 P55212 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26131768 0.89 PBRM1 (0.55) PBRM1DYRK1ALMNAMEN1KMT2A
SCHEMBL29354683 0.84 LMNA (0.56) CA1CA2LMNAMEN1KMT2A
SCHEMBL276018 0.84 LMNA (0.56) CA1CA2LMNAMEN1KMT2A
SCHEMBL29586622 0.84 LMNA (0.56) CA1CA2LMNAMEN1KMT2A
SCHEMBL14598929 0.83 KDM4E (0.62) CA1CA2LMNAMEN1KMT2A
SCHEMBL31490922 0.80 LMNA (0.60) CA1CA2LMNAMEN1KMT2A
SCHEMBL9709372 0.79 ALDH1A1 (0.61) PBRM1DYRK1ALMNAMEN1KMT2A
SCHEMBL31714622 0.79 ALDH1A1 (0.61) PBRM1DYRK1ALMNAMEN1KMT2A
SCHEMBL13833009 0.79 KDM4E (0.67) CA1CA2LMNAMEN1KMT2A
SCHEMBL14543826 0.77 PARP1 (0.59) CA1CA2LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4255996-B1 COMPOSITION FOR REDUCING SLIDING FRICTION OF AN ARTICLE ON SNOW, ICE AND/OR WATER ISANTIN GMBH (CH) 2024-11-20 EP disclosed
EP-4255996-A1 COMPOSITION FOR REDUCING SLIDING FRICTION OF AN ARTICLE ON SNOW, ICE AND/OR WATER ISANTIN GMBH (CH) 2023-10-11 EP disclosed
WO-2022117637-A1 COMPOSITION FOR REDUCING SLIDING FRICTION OF AN ARTICLE ON SNOW, ICE AND/OR WATER ISANTIN GMBH (CH) 2022-06-09 WO disclosed