Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | GLA | P06280 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.56 |
| ▸ | GABRP | O00591 | 1/20 | 0.51 |
| ▸ | GABRD | O14764 | 1/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.51 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31714622 | 1.00 | ALDH1A1 (0.61) | ALDH1A1GAAKDM4EGLAHTT | |
| SCHEMBL26131768 | 0.85 | PBRM1 (0.55) | ALDH1A1GAAKDM4EGLAHTT | |
| SCHEMBL30490061 | 0.84 | GABRP (0.61) | ALDH1A1GAAKDM4EGLAHTT | |
| SCHEMBL6009673 | 0.84 | GABRP (0.61) | ALDH1A1GAAKDM4EGLAHTT | |
| SCHEMBL15746083 | 0.84 | PBRM1 (0.48) | ALDH1A1GAAKDM4EGLAHTT | |
| Ammonia Solution, Strong SCHEMBL28481259 | 0.82 | GABRP (0.59) | ALDH1A1GAAKDM4EGLAHTT | |
| SCHEMBL10345038 | 0.82 | ALDH1A1 (0.74) | ALDH1A1GAAKDM4EGLAHTT | |
| SCHEMBL31619545 | 0.79 | ERCC5 (0.53) | GAALMNAPBRM1DYRK1AGABRP | |
| SCHEMBL6009055 | 0.79 | ERCC5 (0.53) | GAALMNAPBRM1DYRK1AGABRP | |
| SCHEMBL26129641 | 0.79 | PBRM1 (0.47) | ALDH1A1GAAKDM4EGLAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108912047-A | The synthetic method of acridone derivatives | 广州中医药大学(广州中医药研究院) | 2018-11-30 | — | — | CN | disclosed |
| EP-0471516-A1 | Tricyclic heterocyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-19 | — | — | EP | disclosed |
| EP-0110298-B1 | ACRIDANONE DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1988-06-01 | — | — | EP | disclosed |
| US-4711889-A | Schistosomicidal acridanone hydrazones | HOFFMAN-LA ROCHE INC. (US) | 1987-12-08 | — | — | US | disclosed |
| EP-0110298-A1 | Acridanone derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-06-13 | — | — | EP | disclosed |
| US-4244954-A | Acridine compounds and methods of combatting viruses with them | STERLING DRUG INC. (US) | 1981-01-13 | — | — | US | disclosed |
| US-4150134-A | Aminoalkoxy substituted 9(aryl or aralkyl)-acridines | STERLING DRUG INC. (US) | 1979-04-17 | — | — | US | disclosed |