Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 10/20 | 0.51 |
| ▸ | GAA | P10253 | 8/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.44 |
| ▸ | MPI | P34949 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26134880 | 0.74 | LMNA (0.47) | POLBGAARAB9AMAPTKDM4E | |
| SCHEMBL26134884 | 0.74 | LMNA (0.47) | POLBGAARAB9AMAPTKDM4E | |
| SCHEMBL26135603 | 0.74 | LMNA (0.47) | POLBGAARAB9AMAPTKDM4E | |
| SCHEMBL26135639 | 0.72 | GAA (0.65) | POLBGAARAB9ACYP1A2MAPT | |
| SCHEMBL26135297 | 0.72 | GAA (0.65) | POLBGAARAB9ACYP1A2MAPT | |
| SCHEMBL26135296 | 0.72 | GAA (0.65) | POLBGAARAB9ACYP1A2MAPT | |
| SCHEMBL15951402 | 0.69 | POLB (1.00) | POLBGAARAB9AMAPTKDM4E | |
| SCHEMBL6073641 | 0.68 | POLB (0.72) | POLBGAARAB9AMAPTKDM4E | |
| SCHEMBL17927362 | 0.68 | POLB (0.72) | POLBGAARAB9AMAPTKDM4E | |
| SCHEMBL6073638 | 0.68 | POLB (0.72) | POLBGAARAB9AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4499615-A1 | COMPOUNDS USABLE AS MODULATORS OF PERK ACTIVITY | Ramot at Tel-Aviv University Ltd. (IL) | 2025-02-05 | — | — | EP | disclosed |
| WO-2023187783-A1 | COMPOUNDS USABLE AS MODULATORS OF PERK ACTIVITY | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2023-10-05 | — | — | WO | disclosed |