Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PAK4 | O96013 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6952100 | 0.77 | SPR (0.46) | HSD17B10PAK4GSK3BLMNAHTT | |
| SCHEMBL30924204 | 0.77 | SPR (0.46) | HSD17B10PAK4GSK3BLMNAHTT | |
| SCHEMBL26813041 | 0.76 | POLB (0.33) | HSD17B10PAK4NLRP3LMNAHTT | |
| SCHEMBL12703617 | 0.76 | HSD17B10 (0.42) | HSD17B10PAK4GSK3BPDE1BHTT | |
| SCHEMBL31149372 | 0.76 | HSD17B10 (0.42) | HSD17B10PAK4GSK3BPDE1BLMNA | |
| SCHEMBL12703712 | 0.76 | HSD17B10 (0.46) | HSD17B10PAK4GSK3BPDE1BHTT | |
| SCHEMBL28619610 | 0.73 | HSD17B10 (0.40) | HSD17B10PAK4GSK3BPDE1BCHEK1 | |
| SCHEMBL6950131 | 0.73 | HSD17B10 (0.40) | HSD17B10PAK4GSK3BPDE1BCHEK1 | |
| SCHEMBL17680854 | 0.72 | PDE10A (0.39) | HSD17B10GSK3BRETLRRK2 | |
| SCHEMBL15371470 | 0.72 | HSD17B10 (0.39) | HSD17B10GSK3BPDE1BLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4504709-A1 | CDK9 INHIBITORS | Biolexis Therapeutics, Inc. (US) | 2025-02-12 | — | — | EP | disclosed |
| CN-119137103-A | CDK9 inhibitors | 拜奥列司治疗有限公司 | 2024-12-13 | — | — | CN | disclosed |
| US-20240150322-A1 | CDK9 Inhibitors | BAERENKRAFT THERAPEUTICS, LLC | 2024-05-09 | — | — | US | disclosed |
| WO-2023196518-A1 | CDK9 INHIBITORS | Biolexis Therapeutics, Inc. (US) | 2023-10-12 | — | — | WO | disclosed |
| WO-2023196518-A1 | CDK9 INHIBITORS | Biolexis Therapeutics, Inc. (US) | 2023-10-12 | — | — | WO | disclosed |
| CN-108602799-B | Kinase inhibitor | 上海复尚慧创医药研究有限公司 | 2021-08-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240150322-A1 | CDK9 Inhibitors | CDK9, CDK19, CDK1 | HSD17B10 3666/4885PAK4 971/4885GSK3B 172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.