SCHEMBL26144727

SCHEMBL26144727

Cc1c(C)c(OC(=O)C(C)C)c(F)c(F)c1F

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 2/20 0.35
▸ TAS1R3 Q7RTX0 7/20 0.33
▸ TAS1R1 Q7RTX1 7/20 0.33
▸ TAS1R2 Q8TE23 7/20 0.33
▸ GAA P10253 1/20 0.33
▸ IMPDH2 P12268 1/20 0.32
▸ ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26144738 0.94 ELANE (0.36) ELANETAS1R3TAS1R1TAS1R2GAA
SCHEMBL19105005 0.90 TAS1R3 (0.38) ELANETAS1R3TAS1R1TAS1R2GAA
SCHEMBL16848728 0.90 TAS1R3 (0.40) ELANETAS1R3TAS1R1TAS1R2GAA
SCHEMBL11915792 0.88 ELANE (0.42) ELANEGAAALOX15
SCHEMBL19105215 0.74 PKM (0.32) —
SCHEMBL22381449 0.74 GAA (0.37) ELANEGAAALOX15
SCHEMBL12213944 0.72 MAPT (0.42) ELANEGAAALOX15
SCHEMBL23228270 0.72 FABP3 (0.35) ELANE
SCHEMBL26316856 0.72 ELANE (0.34) ELANE
SCHEMBL5495073 0.71 CA1 (0.33) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11649452-B2 High density sequencing and multiplexed priming Singular Genomics Systems, Inc. (US) 2023-05-16 — — US disclosed
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