SCHEMBL2614744

SCHEMBL2614744

CCOc1cc2c3cc(OCC)c(OCC)cc3c3cc(OCC)c(OCC)cc3c2cc1OCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.48
CYP3A4 P08684 3/20 0.48
ENPP1 P22413 1/20 0.46
LMNA P02545 2/20 0.45
ALDH1A1 P00352 4/20 0.44
MAPK1 P28482 3/20 0.44
KDM4E B2RXH2 3/20 0.44
HSD17B10 Q99714 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
MAPT P10636 2/20 0.44
POLB P06746 1/20 0.44
HPGD P15428 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
NQO1 P15559 1/20 0.43
PDE3A Q14432 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
CYP1A2 P05177 2/20 0.42
ADRA2A P08913 1/20 0.42
ADORA3 P0DMS8 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12627598 0.89 ALDH1A1 (0.46) TSHRCYP3A4ENPP1LMNAALDH1A1
SCHEMBL11491934 0.87 TSHR (0.58) TSHRCYP3A4ENPP1LMNAALDH1A1
SCHEMBL28060770 0.82 LMNA (0.47) TSHRCYP3A4LMNAALDH1A1MAPK1
SCHEMBL1779822 0.82 TSHR (0.41) TSHRCYP3A4ENPP1LMNAALDH1A1
SCHEMBL1777257 0.80 KDM4E (0.50) TSHRENPP1ALDH1A1MAPK1KDM4E
SCHEMBL12051760 0.79 TSHR (0.46) TSHRCYP3A4LMNAALDH1A1MAPK1
SCHEMBL13296145 0.78 ALDH1A1 (0.39) TSHRCYP3A4ENPP1LMNAALDH1A1
SCHEMBL13197727 0.77 MAPK1 (0.41) TSHRCYP3A4ENPP1LMNAALDH1A1
SCHEMBL15462599 0.77 ENPP1 (0.47) TSHRCYP3A4ENPP1ALDH1A1MAPK1
SCHEMBL28662301 0.77 KDM4E (0.57) TSHRCYP3A4ENPP1MAPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8623476-B2 Polarizing element and method of producing the same FUJIFILM CORPORATION (JP) 2014-01-07 US disclosed
US-8477275-B2 Optical film and liquid crystal display device FUJIFILM CORPORATION (JP) 2013-07-02 US disclosed
US-8241749-B2 Barrier laminate, gas barrier film, and device using the same FUJIFILM CORPORATION (JP) 2012-08-14 US disclosed
US-20120092594-A1 OPTICAL FILM AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-04-19 US disclosed
US-7872716-B2 Optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2011-01-18 US disclosed
US-20100134726-A1 POLARIZING ELEMENT AND METHOD OF PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2010-06-03 US disclosed
US-20100068537-A1 BARRIER LAMINATE, GAS BARRIER FILM, AND DEVICE USING THE SAME FUJIFILM CORPORATION (JP) 2010-03-18 US disclosed
US-20080192191-A1 Optical Compensation Film, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed
US-7315341-B2 Liquid crystal display device with retardation layer with different relative humidity FUJIFILM CORPORATION (JP) 2008-01-01 US disclosed