Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10967724 | 0.87 | LMNA (0.57) | LMNATSHRHSD17B10HPGDMAPT | |
| SCHEMBL2614744 | 0.82 | TSHR (0.48) | LMNATSHRHSD17B10HPGDMAPT | |
| SCHEMBL9011621 | 0.79 | THRA (0.43) | HPGDMAPTL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL16431851 | 0.77 | HSD17B10 (0.48) | LMNATSHRHSD17B10HPGDMAPT | |
| SCHEMBL19777817 | 0.77 | LMNA (0.48) | LMNATSHRHSD17B10HPGDMAPT | |
| SCHEMBL12187513 | 0.77 | LMNA (0.63) | LMNATSHRHSD17B10HPGDMAPT | |
| SCHEMBL12485109 | 0.77 | THRA (0.46) | LMNAMAPTHTR2BMEN1KMT2A | |
| SCHEMBL9011573 | 0.77 | THRA (0.43) | HPGDMAPTL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL12483379 | 0.77 | THRA (0.46) | LMNAMAPTHTR2BMEN1KMT2A | |
| SCHEMBL23326296 | 0.76 | LMNA (0.52) | LMNATSHRHSD17B10HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105503897-A | Asymmetric benzophenanthrene tri-furan/thiophene, derivate thereof and preparation method | UNIV EAST CHINA NORMAL | 2016-04-20 | — | — | CN | disclosed |