⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24637992 | 0.83 | HSD11B1 (0.34) | — | |
| SCHEMBL7859490 | 0.82 | HTR4 (0.33) | — | |
| SCHEMBL23696204 | 0.81 | PIK3CD (0.36) | — | |
| SCHEMBL18806173 | 0.78 | — | — | |
| SCHEMBL24996457 | 0.78 | — | — | |
| SCHEMBL24794247 | 0.78 | — | — | |
| SCHEMBL22794823 | 0.78 | PIK3CD (0.47) | — | |
| SCHEMBL7696092 | 0.77 | LMNA (0.40) | — | |
| SCHEMBL23365960 | 0.77 | LMNA (0.40) | — | |
| SCHEMBL25084165 | 0.77 | LMNA (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150974-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-05-18 | — | — | US | disclosed |
| US-20230150974-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2023-05-18 | — | — | US | disclosed |