Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.58 |
| ▸ | RAB9A | P51151 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | MEN1 | O00255 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | ALPL | P05186 | 1/20 | 0.58 |
| ▸ | ALPI | P09923 | 1/20 | 0.58 |
| ▸ | ALPG | P10696 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3777988 | 0.85 | RAB9A (0.55) | KDM4ERAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL3771904 | 0.85 | APP (0.55) | KDM4ERAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL3774405 | 0.82 | APP (0.58) | KDM4ERAB9AALDH1A1MEN1KMT2A | |
| Exfoliazone SCHEMBL30080694 | 0.82 | RAB9A (0.47) | KDM4ERAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL2609271 | 0.76 | MAPT (0.68) | KDM4ERAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL2609270 | 0.76 | MAPT (0.68) | KDM4ERAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL28735080 | 0.76 | KDM4E (0.62) | KDM4ERAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL9326807 | 0.76 | MEN1 (0.63) | KDM4ERAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL1635805 | 0.75 | RAB9A (0.49) | KDM4ERAB9AALDH1A1MEN1KMT2A | |
| SCHEMBL2609261 | 0.74 | MAPT (1.00) | KDM4ERAB9AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009003625-A1 | AMINOPHENOXAZINONE AS AN ANTI-TUMOUR AND ANTI-INFLAMMATORY AGENT | EBERHARD-KARLS-UNIVERSITAET TUEBINGEN UNIVERSITAETSKILINIKUM (DE) | 2009-01-08 | — | — | WO | claimed |
| US-8559093-B2 | Electrochromic mirror reflective element for vehicular rearview mirror assembly | DONNELLY CORPORATION (US) | 2013-10-15 | — | — | US | disclosed |
| US-20130063802-A1 | VARIABLE TRANSMISSION WINDOW | DONNELLY CORPORATION (US) | 2013-03-14 | — | — | US | disclosed |
| US-8294975-B2 | Automotive rearview mirror assembly | DONNELLY CORPORATION (US) | 2012-10-23 | — | — | US | disclosed |
| US-20120206790-A1 | ELECTROCHROMIC MIRROR REFLECTIVE ELEMENT FOR VEHICULAR REARVIEW MIRROR ASSEMBLY | DONNELLY CORPORATION (US) | 2012-08-16 | — | — | US | disclosed |
| US-8164817-B2 | Method of forming a mirrored bent cut glass shape for vehicular exterior rearview mirror assembly | DONNELLY CORPORATION (US) | 2012-04-24 | — | — | US | disclosed |
| US-20110045172-A1 | METHOD OF FORMING A MIRRORED BENT CUT GLASS SHAPE FOR VEHICULAR EXTERIOR REARVIEW MIRROR ASSEMBLY | DONNELLY CORPORATION (US) | 2011-02-24 | — | — | US | disclosed |
| US-20100324285-A1 | ANTIINFLAMMATORY AGENT COMPRISING 2-AMINOPHENOL OR DERIVATIVE THEREOF AS ACTIVE INGREDIENT | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2010-12-23 | — | — | US | disclosed |
| US-7821697-B2 | Exterior reflective mirror element for a vehicular rearview mirror assembly | DONNELLY CORPORATION (US) | 2010-10-26 | — | — | US | disclosed |
| US-7821697-B2 | Exterior reflective mirror element for a vehicular rearview mirror assembly | DONNELLY CORPORATION (US) | 2010-10-26 | — | — | US | disclosed |
| US-20080291522-A1 | EXTERIOR REFLECTIVE MIRROR ELEMENT FOR A VEHICLE REARVIEW MIRROR ASSEMBLY | DONNELLY CORPORATION (US) | 2008-11-27 | — | — | US | disclosed |
| US-20080291522-A1 | EXTERIOR REFLECTIVE MIRROR ELEMENT FOR A VEHICLE REARVIEW MIRROR ASSEMBLY | DONNELLY CORPORATION (US) | 2008-11-27 | — | — | US | disclosed |
| US-20080094685-A1 | VEHICULAR EXTERIOR MIRROR | DONNELLY CORPORATION (US) | 2008-04-24 | — | — | US | disclosed |
| US-20080094685-A1 | VEHICULAR EXTERIOR MIRROR | DONNELLY CORPORATION (US) | 2008-04-24 | — | — | US | disclosed |
| US-7349144-B2 | Exterior electrochromic reflective mirror element for a vehicular rearview mirror assembly | DONNELLY CORPORATION (US) | 2008-03-25 | — | — | US | disclosed |
| US-7349144-B2 | Exterior electrochromic reflective mirror element for a vehicular rearview mirror assembly | DONNELLY CORPORATION (US) | 2008-03-25 | — | — | US | disclosed |
| US-20070184284-A1 | Exterior electrochromic reflective mirror element for a vehicular rearview mirror assembly | DONNELLY CORPORATION (US) | 2007-08-09 | — | — | US | disclosed |
| US-20070184284-A1 | Exterior electrochromic reflective mirror element for a vehicular rearview mirror assembly | DONNELLY CORPORATION (US) | 2007-08-09 | — | — | US | disclosed |
| US-7202987-B2 | Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices | DONNELLY CORPORATION (US) | 2007-04-10 | — | — | US | disclosed |
| US-7202987-B2 | Electrochromic polymeric solid films, manufacturing electrochromic devices using such solid films, and processes for making such solid films and devices | DONNELLY CORPORATION (US) | 2007-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324285-A1 | ANTIINFLAMMATORY AGENT COMPRISING 2-AMINOPHENOL OR DERIVATIVE THEREOF AS ACTIVE INGREDIENT | PTGES2, PTGS2, PTGES | KDM4E 1347/4885RAB9A 4632/4885ALDH1A1 535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.