Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 3/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | CCRL2 | O00421 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26170570 | 0.89 | BRD4 (0.40) | CCR5L3MBTL3L3MBTL1DPP4DPP9 | |
| SCHEMBL800697 | 0.81 | HTT (0.45) | CCR5L3MBTL1DPP4DPP9HTR2A | |
| SCHEMBL16219008 | 0.80 | DPP4 (0.47) | CCR5DPP4DPP9PREPFAP | |
| SCHEMBL23798138 | 0.80 | BRD4 (0.41) | CCR5DPP4DPP9KCNH2PREP | |
| SCHEMBL26149396 | 0.79 | PDE7A (0.42) | CCR5L3MBTL3L3MBTL1DPP4KCNH2 | |
| SCHEMBL19419455 | 0.79 | NPY5R (0.43) | CCR5L3MBTL3DPP4DPP9MCHR1 | |
| SCHEMBL18907363 | 0.78 | DPP4 (0.42) | CCR5DPP4DPP9PREPFAP | |
| SCHEMBL23696551 | 0.77 | CCR5 (0.47) | CCR5DPP4DPP9HTR2ASIGMAR1 | |
| SCHEMBL17589227 | 0.77 | CCR5 (0.38) | CCR5L3MBTL3DPP4DPP9PREP | |
| SCHEMBL12304280 | 0.77 | ADH1C (0.42) | CCR5DPP4DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083330-A1 | DRAK2 INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 百极优棠(广东)医药科技有限公司 | 2023-05-19 | — | — | WO | disclosed |