Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19658595 | 0.92 | PDE7A (0.43) | PDE7AL3MBTL3L3MBTL1DPP4DPP8 | |
| SCHEMBL176112 | 0.85 | LMNA (0.39) | PDE7AL3MBTL3L3MBTL1DPP4DPP8 | |
| SCHEMBL14302742 | 0.81 | HRH3 (0.38) | DPP4DPP8KCNH2MCHR1MAP4K4 | |
| SCHEMBL16365471 | 0.81 | HTR6 (0.39) | PDE7AL3MBTL3L3MBTL1DPP4DPP8 | |
| SCHEMBL26149354 | 0.80 | L3MBTL3 (0.36) | PDE7AL3MBTL3L3MBTL1LMNAKDM4E | |
| SCHEMBL26149352 | 0.79 | CCR5 (0.39) | PDE7AL3MBTL3L3MBTL1DPP4CCR5 | |
| SCHEMBL805270 | 0.79 | LMNA (0.51) | L3MBTL1DPP4DPP8LMNAKDM4E | |
| SCHEMBL12010866 | 0.79 | MCHR1 (0.47) | L3MBTL1LMNAALDH1A1KCNH2MCHR1 | |
| SCHEMBL27736476 | 0.78 | L3MBTL3 (0.36) | PDE7AL3MBTL3L3MBTL1LMNAKDM4E | |
| SCHEMBL13207185 | 0.78 | MCHR1 (0.42) | L3MBTL3L3MBTL1DPP4DPP8CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023083330-A1 | DRAK2 INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 百极优棠(广东)医药科技有限公司 | 2023-05-19 | — | — | WO | disclosed |