SCHEMBL2614955

SCHEMBL2614955

CCOCOCCn1c(=O)n(C)c(=O)n(C)c1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 2/20 0.38
ADORA2B P29275 2/20 0.38
ALDH1A1 P00352 4/20 0.37
PKM P14618 1/20 0.37
PDE4A P27815 1/20 0.36
PDE4B Q07343 1/20 0.36
PDE4C Q08493 1/20 0.36
PDE4D Q08499 1/20 0.36
HSD17B10 Q99714 1/20 0.35
HPGD P15428 1/20 0.35
GAA P10253 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
MAPT P10636 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
MAPK1 P28482 1/20 0.34
RECQL P46063 1/20 0.33
HTT P42858 2/20 0.32
RGS4 P49798 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29048899 0.79 ADORA2A (0.49) ADORA2AADORA2BALDH1A1PKMPDE4A
SCHEMBL837375 0.71 MEN1 (0.43) ADORA2AADORA2BALDH1A1PDE4APDE4B
SCHEMBL13133746 0.71 ALDH1A1 (0.44) ADORA2AADORA2BALDH1A1PKMPDE4A
SCHEMBL24684881 0.69 ADORA2A (0.44) ADORA2AADORA2BPDE4APDE4BPDE4C
SCHEMBL13839599 0.67 ALDH1A1 (0.47) ADORA2AADORA2BALDH1A1PDE4APDE4B
SCHEMBL13223313 0.66 RGS4 (0.52) ADORA2APDE4APDE4BPDE4CPDE4D
SCHEMBL19104655 0.66 ALDH1A1 (0.41) ADORA2AADORA2BALDH1A1PDE4APDE4B
SCHEMBL29001108 0.65 HTT (0.32) HTT
SCHEMBL5694827 0.65 ALDH1A1 (0.42) ALDH1A1
SCHEMBL13108310 0.65 PDE4A (0.48) ADORA2AADORA2BPDE4APDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9541848-B2 Electrophotographic photoreceptor Konica Minolta, Inc. (JP) 2017-01-10 US disclosed
US-20160231658-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMING APPARATUS Konica Minolta, Inc. (JP) 2016-08-11 US disclosed
US-9304417-B2 Electrophotographic photoreceptor, electrophotographic image forming apparatus and process cartridge Konica Minolta, Inc. (JP) 2016-04-05 US disclosed
US-20150355560-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR Konica Minolta, Inc. (JP) 2015-12-10 US disclosed
US-20140377694-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE Konica Minolta, Inc. (JP) 2014-12-25 US disclosed
US-8557486-B2 Organic photoreceptor, manufacturing method of organic photoreceptor, and image forming apparatus KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2013-10-15 US disclosed
US-8318396-B2 Organic photoreceptor and preparation method thereof KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2012-11-27 US disclosed
US-8202675-B2 Electrophotographic photoreceptor, image forming apparatus, and process cartridge KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2012-06-19 US disclosed
US-8163456-B2 Image forming method and image forming apparatus KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2012-04-24 US disclosed
US-8084172-B2 Organic photoreceptor, image forming apparatus, process cartridge, and color image forming apparatus KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-12-27 US disclosed
US-20110039197-A1 ORGANIC PHOTORECEPTOR AND PREPARATION METHOD THEREOF KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-02-17 US disclosed
US-20100216065-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2010-08-26 US disclosed
US-20100150610-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMING APPARATUS KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2010-06-17 US disclosed
US-20100129115-A1 ORGANIC PHOTORECEPTOR, MANUFACTURING METHOD OF ORGANIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2010-05-27 US disclosed
US-7700255-B2 Intermediate transfer material, image forming method and image forming apparatus KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2010-04-20 US disclosed
US-20100086328-A1 ORGANIC PHOTORECEPTOR, MANUFACTURING METHOD OF ORGANIC PHOTORECEPTOR, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2010-04-08 US disclosed
US-20090286175-A1 ORGANIC PHOTORECEPTOR, IMAGE FORMING APPARATUS, PROCESS CARTRIDGE, AND COLOR IMAGE FORMING APPARATUS KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-11-19 US disclosed
US-20090258312-A1 IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2009-10-15 US disclosed
US-20080063960-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2008-03-13 US disclosed
US-20070253752-A1 INTERMEDIATE TRANSFER MATERIAL, IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-11-01 US disclosed